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Home / Primary Antibodies / Polyclonal Antibodies

Anti-PDGF beta/PDGFB Antibody Picoband®

SKU : BHA21001139

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Mfr.No.	A00348, A00348-10ug, A00348-Biotin, A00348-Cy3, A00348-Dylight488, A00348-Dylight550, A00348-Dylight594, A00348-FITC, A00348-HRP, A00348-APC, A00348-PE, A00348-iFluor647, A00348-carrier-free
Alternative Names	Platelet-derived growth factor subunit B
Background	Platelet-derived growth factor subunit B is a protein that in humans is encoded by the PDGFB gene. The protein encoded by this gene is a member of the platelet-derived growth factor family. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. This gene is mapped to 22q13.1. Growth factor plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. This gene plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-PDGF beta/PDGFB Antibody Picoband® catalog # A00348. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericy
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human PDGF beta, different from the related mouse and rat sequences by three amino acids.
Isotype	Rabbit IgG
Molecular Weight	27 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Platelet-derived growth factor subunit B;PDGF subunit B;PDGF-2;Platelet-derived growth factor B chain;Platelet-derived growth factor beta polypeptide;Proto-oncogene c-Sis;Becaplermin;PDGFB;PDGF2, SIS;
Tissue Specificity	Expressed at high levels in the heart, brain (sustantia nigra), placenta and fetal kidney. Expressed at moderate levels in the brain (hippocampus), skeletal muscle, kidney and lung. .
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na<sub>2</sub>HPO<sub>4</sub>, 0.05mg NaN<sub>3</sub>.

Uniprot	P01127
Gene Id	5155
Gene Name	PDGFB
Subcellular Location	Secreted. Released by platelets upon wounding.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Mouse, Rat, Human<br>

Reference	1. Bolger, G. B., Stamberg, J., Kirsch, I. R., Hollis, G. F., Schwarz, D. F., Thomas, G. H. Chromosomal translocation t(14;22) and oncogene (c-sis) variant in a pedigree with familial meningioma. New Eng. J. Med. 312: 564-567, 1985. <br /><br />2. Chen, C.-N., Li, Y.-S. J., Yeh, Y.-T., Lee, P.-L., Usami, S., Chien, S., Chiu, J.-J. Synergistic roles of platelet-derived growth factor-BB and interleukin-1-beta in phenotypic modulation of human aortic smooth muscle cells. Proc. Nat. Acad. Sci. 103: 2665-2670, 2006. <br /><br />

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001139-1	A00348	100 ug	-	$370		Add to Cart
BHA21001139-2	A00348-10ug	10 ug	Sample	$99		Add to Cart
BHA21001139-3	A00348-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21001139-4	A00348-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21001139-5	A00348-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21001139-6	A00348-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21001139-7	A00348-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21001139-8	A00348-FITC	100 ug	FITC	$570		Add to Cart
BHA21001139-9	A00348-HRP	100 ug	HRP	$570		Add to Cart
BHA21001139-10	A00348-APC	100 ug	APC	$670		Add to Cart
BHA21001139-11	A00348-PE	100 ug	PE	$670		Add to Cart
BHA21001139-12	A00348-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21001139-13	A00348-carrier-free	100 ug	carrier-free	$370		Add to Cart

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