Anti-SN38 Mouse mAb

Description
Review(s)

Mfr.No.

31905ES60, 31905ES80

Description

SN38 is the active metabolite of the chemotherapy drug irinotecan (Camptosar). It is a topoisomerase I inhibitor, prevents the enzyme from properly resealing the DNA strands after they have been unwound, which leads to the accumulation of DNA damage.

Specifications

Cat.No.	31905ES60/31905ES80
Size	100 ?g/1 mg
Source	Monoclonal anti-SN38 antibody, is produced from a hybridoma which was obtained from a mouse immunized with SN38.
Buffer	1×PBS, pH7.4.
Type	Monoclonal Antibody
Isotype	IgG₁
Host	Mouse
Concentration	1 mg/mL
Purity	?95% as determined by reduced SDS-PAGE ?99% as determined by non-reduced SDS-PAGE > 99% as determined by SEC-HPLC
Activity	EC₅₀=80.5 ng/mL by ELISA
Application	ELISA

Storage

This product should be stored at -25~-15? for one year, do not freeze.

Notes

This product is for research use only.
Please operate with lab coats and disposable gloves, for your safety.

Data

SDS-PAGE

Anti-SN-38 mouse mAb on SDS-PAGE under reduced condition. The purity is 95.5%?

Anti-SN-38 mouse mAb on SDS-PAGE under non-reduced condition. The purity is 99.2%.

SEC-HPLC

The purity of Anti-SN-38 mouse mAb is 100% as determined by SEC-HPLC.

ELISA Data

Dose response curve shows that the EC₅₀ of Anti-SN-38 mouse mAb is 80.5 ng/mL.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHS20800256-1	31905ES60	100 ug	$395		Add to Cart
BHS20800256-2	31905ES80	1 mg	$3912		Add to Cart