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Home / Primary Antibodies / Monoclonal Antibodies

Anti-Paxillin

SKU : BHA15100323

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BioGenex Laboratories

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Mfr.No.	AN876-5M
Clonality	Monoclonal
Description	Paxillin is a multidomain cytoskeletal protein with a role in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Paxillins C- terminal region consist of four LIM domains that interacts with cytoplasmic tail of beta-integrin to target paxillin to focal adhesion. The signaling activity of is controlled by N-terminus of Paxillin. Epithelial cells of various tissues, neuronal cells and mesenchymal derived cells express Paxillin. It has been reported that Paxillin is involved in tumor invasion and metastasis. Its expression in lung and liver cancers has been correlated with advanced tumor stage and metastasis. An antibody to Paxillin is helpful in differentiating between renal cell carcinoma (Paxillin negative) and chromophobe renal cell carcinoma or renal oncocytoma (Paxillin positive), which are rare renal tumors originating from the intercalated cells of collecting ducts
Host	Rabbit
Isotype	IgG
Reactivity	Human
Species	Rabbit

Antigen	Paxillin
Clone No	EP89
Research Area	Infectious diseases, Immune system

Buffer	PBS
Concentration	1-3ug/ml
Storage	2-8°C

Applications	IHC
Dilution	1:50-80

Product Manual	Datasheet SDS

No Description Available.

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Combination SKU	Supplier No.	Size	Your price	Quantity
AN876-5M	AN876-5M	6 mL	$251		Add to Cart
AN876-10M	AN876-10M	100 tests - i6000	$446		Add to Cart
AY876-50D	AY876-50D	50 tests - Xmatrx	$263		Add to Cart
AY876-YCD	AY876-YCD	160 tests - Xmatrx	$773		Add to Cart
NU876-UC	NU876-UC	1ml Conc	$591		Add to Cart
NU876-5UC	NU876-5UC	0.5ml Conc	$412		Add to Cart

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