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Home / Primary Antibodies / Monoclonal Antibodies

Anti-Mucin 1 (MUC1)

SKU : BHA15100287

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BioGenex Laboratories

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Mfr.No.	AN813-5M
Clonality	Monoclonal
Description	Mucins are high molecular weight glycosylated proteins, involved in the protection and lubrication of luminal epithelial surfaces. MUC1 is a transmembrane protein involved in several signaling pathways, including Ras, beta-catenin, p120 catenin, p53 and estrogen receptor alpha. Recent studies indicate MUC1 regulates gene expression, it enters the nucleus by complexing with beta-catenin and inside the nucleus it activates T-cell factor/leukocyte enhancing factor 1 transcription factors. MUC1 function as a signal transducer in various cancer progression, tumor invasion by inhibiting the cell-cell and cell-stroma interactions. Studies correlated MUC1 expression with invasive growth of ductal carcinomas (IDC) in the pancreas and cholangiocarcinomas in the liver and also with a non-invasive intraductal papillary mucinous tumors of the pancreas,. Additionally, MUC1 antibody aids in the prediction of the aggressiveness of carcinomas of the breast, stomach, colon, ampulla of Vater and renal cell carcinoma.
Host	Rabbit
Isotype	IgG
Reactivity	Human
Species	Rabbit

Antigen	Mucin 1 (MUC1)
Clone No	EP85
Research Area	Infectious diseases, Immune system

Buffer	PBS
Concentration	1-3ug/ml
Storage	2-8°C

Applications	IHC
Dilution	1:30-50

Product Manual	Datasheet SDS

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Combination SKU	Supplier No.	Size	Your price	Quantity
AN813-5M	AN813-5M	6 mL	$200		Add to Cart
AN813-10M	AN813-10M	100 tests - i6000	$356		Add to Cart
AY813-50D	AY813-50D	50 tests - Xmatrx	$212		Add to Cart
AY813-YCD	AY813-YCD	160 tests - Xmatrx	$586		Add to Cart
NU813-UC	NU813-UC	1ml Conc	$263		Add to Cart
NU813-5UC	NU813-5UC	0.5ml Conc	$183		Add to Cart

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