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Home / Primary Antibodies / Phospho Antibodies

Anti-MAP3K5 Antibody BHA11304711

SKU : BHA11304711

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Mfr.No.	BS6387
Alternative Names	Apoptosis signal regulating kinase 1 ; Apoptosis signal-regulating kinase 1 ; ASK 1 ; ASK-1 ; ASK1 ; M3K5 ; MAP/ERK kinase kinase 5 ; MAP3K5 ; MAPK/ERK kinase kinase 5 ; MAPKKK5 ; MEK kinase 5 ; MEKK 5 ; MEKK5 ; Mitogen activated protein kinase kinase kinase 5 ; Mitogen-activated protein kinase kinase kinase 5
Categories	Primary Antibodies ; Phospho Antibodies
Chromosome Location	6q23.3
Clonality	polyclonal
Description	Mitogen-activated protein (MAP) kinase cascades are activated by various extracellular stimuli including growth factors. The MEK kinases (also called MAP kinase kinase kinases) phosphorylate and activate the MAP kinases, including ERK, JNK and p38. The MEK kinases characterized to date include Raf-1, Raf-B, MOS, MEK kinase-1, MEK kinase-2, MEK kinase-3, MEK kinase-4 and ASK 1 (also designated MEK kinase-5). MEK kinase-1 has been shown to phosphorylate MEK-1 via a Raf-independent pathway. Evidence suggests that MEK-3 is preferentially activated by MEK kinase-3 and that MEK-4 is activated by both MEK kinase-2 and MEK kinase-3. MEK kinase-4 has been shown to specifically activate the JNK pathway. ASK 1 activates both MEK-4 and MEK-3/MEK-6 pathways.
Host	Rabbit
Immunogen	Synthetic phosphopeptide derived from human ASK1 around the phosphorylation site of Threonine 918.
Modification	phospho-T918
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q99683
Uniprot	Q99683
Weight	155 kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: p-ASK1 (T918) polyclonal antibody detects endogenous levels of ASK1 protein only when phosphorylated at Thr918.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:2000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11304711	BS6387	50µl	$252.67		Add to Cart
BHA11304711	BS6387	100µl	$403.78		Add to Cart

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