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Home / Primary Antibodies / Monoclonal Antibodies

Anti-J chain

SKU : BHA15100143

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BioGenex Laboratories

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Mfr.No.	AM374-5M
Clonality	Monoclonal
Description	J chain is a small, glycopeptide of 15 kD. It is structurally unrelated to heavy or light chains, but is synthesized by all plasma cells that secrete polymeric immunoglobulins. J chains are present in a large proportion of the immunoglobulin-positive cells in the germinal centers of the tonsils and lymph nodes. B cells secrete J chain at an early stage of differentiation with the expression persisting in those cells destined to produce IgA or IgM. J chain has been proposed to play a role in the mucosal transport of polymeric Igs by the polymeric Ig receptor. The studies show that a significant proportion of deposited mesangial immunoglobulin in IgA nephropathy is dimeric, or J chain positive. This monoclonal antibody stains J chain in cytoplasm of positve cells. B cells secrete J chain at an early stage of differentiation with the expression persisting in those cells destined to produce IgA or IgM
Host	Mouse
Isotype	IgG1 Kappa
Reactivity	Human
Species	Mouse

Clone No	JC88
Research Area	Infectious diseases, Immune system

Buffer	PBS
Concentration	1-3ug/ml
Storage	2-8°C

Applications	IHC
Dilution	1:10-20

Product Manual	Datasheet SDS

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Combination SKU	Supplier No.	Size	Your price	Quantity
AM374-5M	AM374-5M	6 mL	$293		Add to Cart
AM374-10M	AM374-10M	100 tests - i6000	$518		Add to Cart
AX374-50D	AX374-50D	50 tests - Xmatrx	$305		Add to Cart
AX374-YCD	AX374-YCD	160 tests - Xmatrx	$905		Add to Cart
MU374-UC	MU374-UC	1ml Conc	$310		Add to Cart
MU374-5UC	MU374-5UC	0.5ml Conc	$217		Add to Cart

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