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Home / Primary Antibodies / Phospho Antibodies

Anti-H3F3A/HIST2H3A/HIST1H3A Antibody BHA11302646

SKU : BHA11302646

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Mfr.No.	BS4699
Alternative Names	Histone H3.1 ; H3/a ; H3/b ; H3/c ; H3/d ; H3/f ; H3/h ; H3/i ; H3/j ; H3/k ; H3/l
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	polyclonal
Description	Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fibre is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.Covalent modifications of the canonical core histones, including acetylation, phosphorylation, methylation, and monoubiquitination are used to mark nucleosomes to create chromatin domains with a range of functions.
Host	Rabbit
Immunogen	Synthetic phosphopeptide derived from human Histone H3 around the phosphorylation site of Threonine 11.
Modification	phospho-T11
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO

Swissprot	P68431/Q71DI3/P84243
Uniprot	P68431/Q71DI3/P84243
Weight	17 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: p-Histone H3 (T11) polyclonal antibody detects endogenous levels of Histone H3 protein only when phosphorylated at Thr11. (removal of the initiator methionine)
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IF

Description

WB ; IF

Dilution

WB	1:500-1:1000
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302646	BS4699	50µl	$199.33		Add to Cart
BHA11302646	BS4699	100µl	$314.89		Add to Cart

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