JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
orders@biohippo.com

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Primary Antibodies / Monoclonal Antibodies

Anti-GPRC5D-Anti-CD3 Bispecific Antibody

SKU : BHA18200129

Contact us to order

Tel

+1 866.986.9598

Email

orders@biohippo.com

Get a Quote

Request More Infos

BPS Bioscience

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

orders@biohippo.com

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	102450, 102450-1, 102450-2, 102450-3
Background	The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D) is a retinoic acid-inducible protein with seven transmembrane segments and a short N-terminal extracellular region. The strong and selective expression of GPRC5D in Multiple Myeloma (MM) cells, similar to the expression patte of B-cell maturation antigen (BCMA), makes it a promising target for the treatment of MM. It is anticipated that GPRC5D will be an alteative CAR (chimeric antigen receptor)-T cell target for MM immunotherapy.
Clonality	Monoclonal
Description	Anti-GPRC5D-Anti-CD3 bispecific antibody is a purified recombinant human bispecific antibody with T cell engager. This bispecific antibody has been tested in a functional assay using NFAT Luciferase Reporter Jurkat Cell Line (BPS Bioscience #60621) in the presence of GPRC5D CHO Recombinant Cell Line (BPS Bioscience #78337) that overexpress GPRC5D (G protein–coupled receptor, class C group 5 member D).
Formulation	8 mM phosphate, 110 mM NaCl, 2.2 mM KCl, pH 7.4, and 20% glycerol
Host	HEK293
Isotype	IgG1
Molecular Weight	Heavy Chain: 49 kDa + glycans; Light Chain: 24 kDa
Shipping	-80°C
Species	Human
Synonyms	G-protein coupled receptor family C group 5 member D, GPRC5D, class C group 5 member D, CD3, T cell engager, bispecific, biTE.
Usage	Thaw on ice and gently mix prior to use. DO NOT VORTEX. Perform a quick spin before opening. Aliquot into small volumes and flash freeze for long term storage. Avoid multiple freeze/thaw cycles.
Note	Waings Avoid freeze/thaw cycles. Scientific Category Immunotherapy Regulatory Status Research Use Only Endotoxin Level 0.9 EU/mg Glycosylation This antibody runs at a higher MW by SDS-PAGE due to glycosylation. Assay Conditions This antibody was tested as followed. GPRC5D CHO cells (#78337) were incubated with NFAT Luciferase Reporter Jurkat cells (#60621) in a 96-well plate at a 1:2 ratio. Anti-GPRC5D-Anti-CD3 Bispecific Antibody and the negative control Anti-Claudin18.2-Anti-CD3 IgG Bispecific Antibody (#101541) were serially diluted and added to the cells. After 20 hours, luciferase activity was measured with ONE-Step™ Assay System (#60690) and luminescence was measured in a plate reader.

Concentration	1.62 mg/ml
Format	Aqueous buffer solution.
Purification	Protein A affinity purification from HEK293 cells
Purity	≥90%
Storage	Stable for at least 12 months at -80°C.

Tested Application	Anti-GPRC5D-Anti-CD3 Bispecific Antibody can be used for studying GPRC5D+ cancer cell-mediated T cell activation, using either primary T cells or reporter cell lines such NFAT Luciferase Reporter Jurkat Cell Line (#60621).

No Description Available.

No Description Available.

Have you used this product?

Rate it now..!!

Login to Review

Combination SKU	Supplier No.	Size	Your price	Quantity
BHA18200129-1	102450-1	25 µg	$210		Add to Cart
BHA18200129-2	102450-2	100 µg	$510		Add to Cart
BHA18200129-3	102450-3	1 mg	$2500		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2025 Biohippo. All rights reserved.