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Home / Primary Antibodies / Phospho Antibodies

Anti-CSF2RB Antibody BHA11302391

SKU : BHA11302391

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Mfr.No.	BS4102
Alternative Names	Cytokine receptor common subunit beta ; CDw131 ; GM-CSF/IL-3/IL-5 receptor common beta subunit ; CD131 ; CSF2RB ; IL3RB ; IL5RB ; IL3Rβ
Categories	Primary Antibodies ; Phospho Antibodies
Chromosome Location	22q12.3
Clonality	polyclonal
Description	Interleukin-3, or IL-3, is a pleiotropic cytokine that is primarily secreted by activated T lymphocytes and stimulates the proliferation and differentiation of hematopoietic cells. IL-3 exerts its biological effects through a receptor which consists of a ligand-specific α subunit (IL-3Rα) and a signal transducing β subunit (IL-3Rβ) common to the IL-3/IL-5/GM-CSF receptors. The α subunits are low-affinity ligand-binding proteins while the β subunits do not themselves bind ligand, but are required for high affinity binding by the α subunits. The mouse IL-3 receptor has two distinct β subunits, one that functions only in IL-3-mediated cell signaling and a second that is shared with IL-5 and GM-CSF. The murine β subunits are 91% homologous at the amino acid level but only 56% homologous to the human β subunit.
Host	Rabbit
Immunogen	Synthetic phosphopeptide derived from human IL-3Rβ around the phosphorylation site of Tyrosine 593.
Modification	phospho-Y593
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P32927
Uniprot	P32927
Weight	97, 130 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: p-IL-3Rβ (Y593) polyclonal antibody detects endogenous levels of L-3R protein only when phosphorylated at Tyr593.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302391	BS4102	50µl	$199.33		Add to Cart
BHA11302391	BS4102	100µl	$314.89		Add to Cart

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