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Home / Primary Antibodies / IHC Antibodies

Anti-AKT3/AKT2/AKT1 Antibody BHA11302790

SKU : BHA11302790

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Mfr.No.	BS5050
Alternative Names	RAC-alpha serine/threonine-protein kinase ; Protein kinase B ; PKB ; Protein kinase B alpha ; PKB alpha ; Proto-oncogene c-Akt ; RAC-PK-alpha ; AKT1 ; PKB ; RAC ; PKBα ; RAC-beta serine/threonine-protein kinase ; Protein kinase Akt-2 ; Protein kinase B beta ; PKB beta ; RAC-PK-beta ; AKT2 ; PKBβ ; RAC-gamma serine/threonine-protein kinase ; Protein kinase Akt-3 ; Protein kinase B gamma ; PKB gamma ; RAC-PK-gamma ; STK-2 ; AKT3 ; PKBG ; PKBγ
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	polyclonal
Description	AKT, also known as protein kinase B (PKB), is a 57 kDa serine/threonine protein kinase. There are three mammalian isoforms of Akt: AKT1 (PKB alpha), AKT2 (PKB beta) and AKT3 (PKB gamma) with AKT2 and AKT3 being approximately 82% identical with the AKT1 isoform. Each isoform has a pleckstrin homology (PH) domain, a kinase domain and a carboxy terminal regulatory domain. AKT was originally cloned from the retrovirus AKT8, and is a key regulator of many signal transduction pathways. Its tight control over cell proliferation and cell viability are manifold; overexpression or inappropriate activation of AKT has been seen in many types of cancer.
Host	Rabbit
Immunogen	Synthetic phosphopeptide derived from human AKT1 around the phosphorylation site of Tyrosine 326.
Modification	phospho-Y326
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO

Swissprot	P31749/P31751/Q9Y243
Uniprot	P31749/P31751/Q9Y243
Weight	60 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: p-AKT (Y326) polyclonal antibody detects endogenous levels of AKT1 only when phosphorylated at Tyr326. This antibody also recognizes AKT2 and AKT3 when phosphorylated at the corresponding residues.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

IHC

Description

IHC

Dilution

IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302790	BS5050	50µl	$199.33		Add to Cart
BHA11302790	BS5050	100µl	$314.89		Add to Cart

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