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Prkn-KO

SKU : BHAM00246

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	NM-KO-190335
Description	Model Description: Prkn-KO mice (Stock No.NM-KO-190335)carry a knockout allele derived from the targeted deletion of exon 3. While Prkn-KO(2) mice (Stock No.NM-KO-191005)mice carrying the exon 4 deletion. Official Symbol: Prkn NCBI ID: 50873 MGI ID: 1355296 Ensembl ID: ENSMUSG00000023826 Pubmed: Prkn Human Ortholog: PRKN
Nomenclature	C57BL/6JSmoc-Prkn^em1Smoc
Exon	Exon 3.
Application	Immune-Related
Disease	Parkinson's Disease 2
Disease	Nervous System Disease
KI/KO Gene	Prkn
Synonyms	Park2 Parkin PRKN

Reference	MGI:3832410 Itier JM, Ibanez P, Mena MA, Abbas N, Cohen-Salmon C, Bohme GA, Laville M, Pratt J, Corti O, Pradier L, Ret G, Joubert C, Periquet M, Araujo F, Negroni J, Casarejos MJ, Canals S, Solano R, Serrano A, Gallego E, Sanchez M, Denefle P, Benavides J, Tremp G,Rooney TA, Brice A, Garcia de Yebenes J, Parkin gene inactivation alters behaviour and dopamine neurotransmission in the mouse. Hum Mol Genet. 2003 Sep 15;12(18):2277-91

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