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Lrp1-Flox

SKU : BHAM00162

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	NM-CKO-2101319
Description	Model Description: These mice carry loxP sites flanking exon 7-8 of Lrp1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Lrp1 gene. Official Symbol: Lrp1 NCBI ID: 16971 MGI ID: 96828 Ensembl ID: ENSMUSG00000040249 Pubmed: Lrp1 Human Ortholog: LRP1
Nomenclature	C57BL/6JSmoc-Lrp1^{em1(flox)Smoc}
Exon	Exon 7-8 of
Disease	Cardiomyopathy
Disease	Cardio-metabolic Disease, Nervous System Disease
KI/KO Gene	Lrp1
Notes	Note: The expected phenotype(s) may be observed in the above-mentioned mice that bred with Tagln-cre mice.
Synonyms	Lrp, A2mr, CD91, AI316852, b2b1554Clo

Reference	MGI:5905195 Basford JE, Koch S, Anjak A, Singh VP, Krause EG, Robbins N, Weintraub NL, Hui DY, Rubinstein J, Smooth muscle LDL receptor-related protein-1 deletion induces aortic insufficiency and promotes vascular cardiomyopathy in mice. PLoS One. 2013;8(11):e82026

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