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Home / Animal Model / Disease Mice

Brca2-Flox

SKU : BHAM00036

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	NM-CKO-200014
Description	Model Description: These mice carry loxP sites flanking exon 11 of Brca2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Brca2 gene. Official Symbol: Brca2 NCBI ID: 12190 MGI ID: 109337 Ensembl ID: ENSMUSG00000041147 Pubmed: Brca2 Human Ortholog: BRCA2
Nomenclature	C57BL/6JSmoc-Brca2^{tm1(flox)Smoc}
Exon	Exon 11
Application	Breast Cancer Research
Disease	Breast Cancer
KI/KO Gene	Brca2
Notes	Note: The expected phenotype(s) may be observed in the above-mentioned mice that bred with Wap-cre mice.
Synonyms	Fancd1, RAB163

Reference	MGI:5770244 Ludwig T, Fisher P, Murty V, Efstratiadis A, Development of mammary adenocarcinomas by tissue-specific knockout of Brca2 in mice. Oncogene. 2001 Jul 5;20(30):3937-48

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