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Aldh1L2-KO

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	TBD
Description	Model Description: Exon 2 of Aldh1L2 gene was deleted to generate Aldh1L2 knockout mice. Official Symbol: Aldh1l2 NCBI ID: 216188 MGI ID: 2444680 Ensembl ID: ENSMUSG00000020256 Pubmed: Aldh1l2 Human Ortholog: ALDH1L2
Nomenclature	C57BL/6JSmoc-Aldh1L2^em1Smoc
Exon	Exon 2
Disease	Non-Alcoholic Fatty Liver Disease
Disease	Cardio-metabolic Disease
KI/KO Gene	Aldh1l2
Synonyms	mtFDH, D330038I09Rik

Reference	MGI:6501754 Krupenko NI, Sharma J, Pediaditakis P, Helke KL, Hall MS, Du X, Sumner S, Krupenko SA, Aldh1l2 knockout mouse metabolomics links the loss of the mitochondrial folate enzyme to deregulation of a lipid metabolism observed in rare human disorder. Hum Genomics. 2020 Nov 9;14(1):41

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Aldh1L2-KO

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