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AG129 Mouse Model Research Service by IBT

SKU : BHS20900001

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Mfr.No.	BHS20900001
Provider Location	Rockville, Maryland, USA
Description	AG129 Mouse Model Research Service IBT Bioservices offers comprehensive research support using AG129 mice for infectious disease and immune response studies. Service Overview The AG129 mouse model is a powerful tool for studying infectious diseases and immune responses. Genetically engineered to lack interferon alpha/beta (IFNAR) and gamma (IFNGR) receptors, these mice are highly susceptible to viral infections, providing researchers with an unparalleled platform to study disease mechanisms and therapeutic interventions. Key Features Genetically modified to lack IFNAR and IFNGR, enhancing viral susceptibility. Highly relevant for studying viral pathogenesis and immune responses. Ideal for preclinical evaluation of vaccines and antiviral therapies. Supported by a team of experts in infectious disease research. Accelerating Therapeutic Development AG129 mice play a crucial role in therapeutic research by providing a highly sensitive model to evaluate vaccines, antivirals, and immune-based therapies. The unique absence of interferon signaling pathways allows researchers to better understand viral pathogenesis and immune evasion strategies, paving the way for more targeted and effective treatments. This model has been used extensively to study arboviruses such as Dengue, Zika, and West Nile viruses, as well as highly pathogenic viruses like Ebola and Marburg. By leveraging this model, IBT Bioservices helps clients unlock new opportunities in infectious disease research. Additionally, AG129 mice enable studies in safer BSL-2 settings using pseudoviruses, significantly reducing costs and logistical challenges associated with BSL-3 or BSL-4 facilities. Unlocking Insights in Infectious Disease Research The AG129 mouse model supports groundbreaking research into immune mechanisms, offering critical data on cytokine signaling, viral replication, and host-pathogen dynamics. This enables better understanding of immune suppression and evasion strategies employed by viruses, accelerating discoveries in therapeutic development. Researchers can also utilize this model to study co-infections and complex disease progressions, paving the way for innovative treatment strategies and multi-targeted therapies. Applications Infectious Disease Research: Study arboviruses such as Dengue, Zika, and West Nile viruses. Therapeutic Development: Evaluate vaccines and antiviral candidates for safety and efficacy. Immune Response Analysis: Investigate immune pathways, cytokines, and cell interactions during viral infections. Host-Pathogen Interaction Studies: Examine viral replication and immune evasion strategies in-depth. Co-Infection Modeling: Explore complex interactions in multi-pathogen environments. Why Choose IBT Bioservices? At IBT Bioservices, we combine state-of-the-art facilities and scientific expertise to deliver reliable and insightful research services. Our AG129 Mouse Model Research Service offers: Comprehensive experimental design tailored to your research needs. Compliance with ethical guidelines and high-quality animal handling standards. Cost-effective solutions for advanced preclinical research. Expert analysis of immune responses and viral mechanisms. Dedicated support for data interpretation and reporting. Contact Us Ready to advance your research? Contact IBT Bioservices to lea how our AG129 Mouse Model Research Service can support your next project. Email us at info@ibtbioservices.com. Disclaimer The AG129 Mouse Model is provided exclusively for research purposes. IBT Bioservices ensures all animals are handled in compliance with ethical and regulatory standards.
Keywords/Tags	AG129 Mouse Model Infectious Disease Research Immune Response Studies Viral Pathogenesis Vaccine Development Therapeutic Development Host-Pathogen Interactions Co-Infection Modeling Pseudovirus Studies Preclinical Research Immune Evasion Strategies Antiviral Evaluation Cytokine Signaling Analysis Genetic Mouse Models
Turnaround Time	4-6 months, 6-9 months, 9-12 months
Year Established	2005

Technology Used	Genetic Knockout Technology (IFNAR and IFNGR deletion), Viral Infection Models using Arboviruses (Dengue, Zika, West Nile), Pseudovirus Platforms for BSL-2 Studies, Advanced Cytokine Signaling Analysis Tools, Immune Response Profiling using Flow Cytometry and ELISA

Payment Terms	Net 30
Additional Costs	shipping
Currency Accepted	USD
Refund Policy	non refundable

Certifications	RUO
Quality Control Steps	QC Report, Validation

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