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Home / Primary Antibodies / Monoclonal Antibodies

Aldose reductase Antibody / AKR1B1

SKU : BHA17116150

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NSJ Bioreagents

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Mfr.No.	V7403, V7403-20UG, V7403-100UG
Clonality	Monoclonal
Description	AKR1B1, also deisgnated as aldose reductase, is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This protein catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. It has also been shown to have decreased expression in adrenocortical cancer, and possibly play a role in adrenal tumorigenesis. It has been suggested that AKR1B1 could be investigated as a marker of malignancy for adrenal tumor diagnosis.
Formulation	0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Host	Mouse
Immunogen Region	Recombinant protein was used as the immunogen for this Aldose reductase antibody.
Isotype	IgG1,kappa
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No
Subcellular Location	Cytoplasmic

Antigen	AKR1B1
Uniprot	P15121
Clone No	CPTC-AKR1B1-3

Concentration	0.2 mg/ml
Format	Purified
Purification	Protein G affinity chromatography
Storage	Store the Aldose reductase antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Applications	WB, IF, IHC-P
Dilution	Western blot: 1-2ug/ml,Immunofluorescence: 1-2ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml for 30 min at RT

Product Manual	Data Sheet

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