Zeta-chain (TCR) associated protein kinase 70kDa Adenovirus (Ad-ZAP-70)

Mfr.No.	1423
Description	Syk p72 and ZAP-70 resemble the Src family protein tyrosine kinases in that they have a C-terminal catalytic domain, but differ in that they are characterized by two SH2 domains but no SH3 domains. Syk p72 kinase fused to the transmembrane and extracellular domains of CD7 and CD16, respectively, can induce complete T cell activation, implying the involvement of the Syk/ZAP family proteins in T cell activation. In contrast, the ZAP-70 kinase is insufficient for complete T cell activation unless it is coaggregated with a Fyn p59-containing chimera, suggesting that regulation of ZAP-70 activity may require a functional interaction with Src family kinases.
Categories	Adenovirus, Over-Expression
Product Type	Pre-Made
Virus Type	Adenovirus
Function	Gene expression
Promoter	CMV (ubiquitous)
Storage Buffer	DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone	Human Adenovirus Type5 (dE1/E3)
Shelf Life	12 Months
HS Code	3822190000
UNSPSC Code	41106621
Insert Gene	ZAP-70
Availability	Ready to Ship
Titer	1x10^10 PFU/ml
Storage	-80C
Shipping	Dry Ice

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SKU	Supplier No.	Size	Your price	Quantity
BHV21600121	1423	200 µL	$690		Add to Cart