Toll-like receptors (TLR) are fundamental for pathogen recognition and initiation of the innate immune response. TLRs recognize pathogen contours and mediate the production of cytokines necessary for immunity toward the pathogen. There is a high level of conservation in TLRs, both structurally and functionally, from Drosophila to humans. The TLR family of proteins is characterized by a highly conserved Toll homology (TH) domain, which is essential for Toll-induced signal transduction. Another TLR protein, RP105, is predominately expressed on mature B-cells and has a striking similarity to TLR4.
Categories
Adenovirus, Over-Expression
Product Type
Pre-Made
Virus Type
Adenovirus
Function
Gene expression
Promoter
CMV (ubiquitous)
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)
Shelf Life
12 Months
HS Code
3822190000
UNSPSC Code
41106621
Insert Gene
TLR4
Availability
Ready to Ship
Titer
1x10^10 PFU/ml
Storage
-80C
Shipping
Dry Ice
Reviews of Toll-like receptor 4 Adenovirus (Ad-TLR4)