Genetic and biochemical studies have led to the identification of the Stat3-Interacting Protein STATIP1. The preferential association of STATIP1 with inactive (i.e., unphosphorylated) Stat3 suggests that it may contribute to the regulation of Stat3 activation. Overexpression of the Stat3-binding domain of STATIP1 blocks Stat3 activation, nuclear translocation, and Stat3-dependent induction of a reporter gene.
Categories
Adenovirus, Over-Expression
Product Type
Pre-Made
Virus Type
Adenovirus
Function
Gene expression
Promoter
CMV (ubiquitous)
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)
Shelf Life
12 Months
HS Code
3822190000
UNSPSC Code
41106621
Insert Gene
STAT3IP
Availability
Ready to Ship
Titer
1x10^10 PFU/ml
Storage
-80C
Shipping
Dry Ice
Reviews of STAT3 interacting protein 1 Adenovirus (Ad-STAT3IP)