Mitogen-activated protein kinase 3 Adenovirus (Ad-ERK1)

Mfr.No.	1585
Description	The activation of signal transduction pathways by growth factors, hormones and neurotransmitters is mediated through two closely related MAP kinases, p44 and p42, which are encoded by ERK 1 and ERK 2, respectively. Both proteins are regulated by dual phosphorylation on specific tyrosine and threonine residues mapping within a characteristic Thr-Glu-Tyr motif. In response to activation, both MAP kinases phosphorylate downstream components on serine and threonine. Upstream MAP kinase regulators include MAP kinase kinase (MEK), MEK kinase and Raf-1. ERK 3 is a MAP kinase-related protein. The human homolog of ERK 3 has also been cloned and shown to encode a 97 kDa protein. ERK 5 has been identified as an 815 amino acid protein that functions as a substrate for MEK-5, but not for MEK-1 or MEK-2. ERK 6 (also designated SAPK3) is highly expressed in human skeletal muscle and appears to function as a signal transducer during differentiation of myoblasts to myotubes.
Categories	Adenovirus, Over-Expression
Product Type	Pre-Made
Virus Type	Adenovirus
Function	Gene expression
Promoter	CMV (ubiquitous)
Storage Buffer	DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone	Human Adenovirus Type5 (dE1/E3)
Shelf Life	12 Months
HS Code	3822190000
UNSPSC Code	41106621
Insert Gene	ERK1
Availability	Ready to Ship
Titer	1x10^10 PFU/ml
Storage	-80C
Shipping	Dry Ice

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SKU	Supplier No.	Size	Your price	Quantity
BHV21600278	1585	200 µL	$690		Add to Cart