Jun B proto-oncogene Adenovirus (Ad-JUN B)

Mfr.No.	1535
Description	The activator protein-1 (AP-1) transcription factor consists of either Jun homodimers or Fos/Jun heterodimeric complexes, which bind the palindromic TRE sequence TGA(C/G)TCA. The Jun family includes c-Jun, Jun B and Jun D, while the Fos gene family members include c-Fos, Fos B, Fra-1 and Fra-2. In addition, certain ATF/CREB proteins form leucine zipper dimers with Fos and Jun, which exhibit different specificities for AP-1 and CRE DNA motifs. AP-1 transcription factor components are subject to regulation by both phosphorylation and by chemical oxidation of specific cysteine residues mapping within the DNA binding domains of Fos and Jun. Oxidation is reversible by a cellular redox/DNA repair protein designated Ref-1 (redox factor 1). JAB1 (Jun-activation domain-binding protein 1) potentiates transcription by either c-Jun or Jun D.
Categories	Adenovirus, Over-Expression
Product Type	Pre-Made
Virus Type	Adenovirus
Function	Gene expression
Promoter	CMV (ubiquitous)
Storage Buffer	DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone	Human Adenovirus Type5 (dE1/E3)
Shelf Life	12 Months
HS Code	3822190000
UNSPSC Code	41106621
Insert Gene	JUN B
Availability	Ready to Ship
Titer	1x10^10 PFU/ml
Storage	-80C
Shipping	Dry Ice

Have you used this product?

SKU	Supplier No.	Size	Your price	Quantity
BHV21600230	1535	200 µL	$690		Add to Cart