Interleukin-1 receptor-associated kinase 3 Adenovirus (Ad-IRAK3)

Mfr.No.	1439
Description	Interleukin-1 receptor (IL1R)-associated kinases (IRAKs) are important mediators in the signal transduction of Toll-like receptor (TLR) and IL-1R family members, collectively referred to as TIRs. Binding of IL-1 to its cognate receptor results in the activation of the NFkB signaling pathway. 100kDa IRAK-1 is implicated as an upstream mediator of NFkB activation. IRAK-2 is a proximal mediator of IL-1, a component of the IL-1R signaling complex and is required for IL-1R-induced NF?B activation. IRAK-4 is strongly expressed in kidney and is also found in lung, testis, small intestine, breast, liver, and placenta. In contrast to the other IRAKs that are expressed in most cell types, IRAK-M is restricted to monocytic cells.
Categories	Adenovirus, Over-Expression
Product Type	Pre-Made
Virus Type	Adenovirus
Function	Gene expression
Promoter	CMV (ubiquitous)
Storage Buffer	DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone	Human Adenovirus Type5 (dE1/E3)
Shelf Life	12 Months
HS Code	3822190000
UNSPSC Code	41106621
Insert Gene	IRAK3
Availability	Ready to Ship
Titer	1x10^10 PFU/ml
Storage	-80C
Shipping	Dry Ice

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SKU	Supplier No.	Size	Your price	Quantity
BHV21600137	1439	200 µL	$690		Add to Cart