FK506 binding protein 1A, 12kDa Adenovirus (Ad-FKBP12)

Mfr.No.	1514
Description	The immunophilins are a highly conserved family of cis-trans peptidyl-prolyl isomerases that bind to and mediate the effects of immunosuppressive drugs, such as cyclosporin, FK506 and rapamycin. Several related immunophilins, FKBP12, FKBP51 and FKBP52 are characterized as cytosolic FK506-binding proteins. Following ligand binding, they functionally inhibit the phosphatase activity of calcineurin. These related proteins have distinct molecular masses and differential expression patterns. FKBP12 and FKBP52 are both widely expressed and have molecular masses of 12 kDa and 52 kDa, respectively. FKBP51 is a 51 kDa protein that is predominantly expressed in T cells, where it blocks T cell activation.
Categories	Adenovirus, Over-Expression
Product Type	Pre-Made
Virus Type	Adenovirus
Function	Gene expression
Promoter	CMV (ubiquitous)
Storage Buffer	DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone	Human Adenovirus Type5 (dE1/E3)
Shelf Life	12 Months
HS Code	3822190000
UNSPSC Code	41106621
Insert Gene	FKBP12
Availability	Ready to Ship
Titer	1x10^10 PFU/ml
Storage	-80C
Shipping	Dry Ice

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SKU	Supplier No.	Size	Your price	Quantity
BHV21600209	1514	200 µL	$690		Add to Cart