The accumulation of diacylglycerol in the nucleus is important for the regulation of cell growth and differentiation. Diacylglycerol kinases (DGKs) convert diacylglycerol to phosphatidic acid, thereby terminating diacylglycerol signaling, which results in the reduction of protein kinase C activity and cell cycle progression of T-lymphocytes. Diacylglycerol kinases are divided into five subtypes, Type I - Type V. DGK-α, DGK-β and DGK-γ are Type I DGKs; DGK-δ and DGK-η are Type II DGKs; DGK-ε is a Type III DGK; DGK-ζ is a Type IV DGK; and DGK-θ is a Type V DGK.
Categories
Adenovirus, Over-Expression
Product Type
Pre-Made
Virus Type
Adenovirus
Function
Gene expression
Promoter
CMV (ubiquitous)
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)
Shelf Life
12 Months
HS Code
3822190000
UNSPSC Code
41106621
Insert Gene
DGKa
Availability
Ready to Ship
Titer
1x10^10 PFU/ml
Storage
-80C
Shipping
Dry Ice
Reviews of Diacylglycerol kinase, alpha 80kDa Adenovirus (Ad-DGKa)