Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.
Formulation
In ascites with 0.09% sodium azide
Host
Mouse
Immunogen Region
A portion of amino acids 1-270 from the human protein was used as the immunogen for this ACE2 antibody.
Isotype
Mouse IgM
Species Reactivity
Human
Note
Titration of the ACE2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Uniprot
Q9BYF1
Format
Ascites
Purity
Ascites
Storage
Aliquot the ACE2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.