Cre recombinase is used as a tool to genetically modify genes, such as to delete a segment of DNA flanked by LoxP sites in cells or experimental animals.By applying the mammalian codon usage to Cre recombinase, expression of Cre is improved in the mammalian cells. This improved Cre (iCre) gene also reduce the high CpG content of the prokaryotic coding sequence, thereby reducing the chances of epigenetic silencing in mammals.This AAV-DJ8 stock expresses an improved Cre (iCre) under a liver-specific Ttr promoter
Categories
AAV, Over-Expression, Cre Recombinases
Product Type
Pre-Made
Virus Type
AAV
Function
Recombinase
Promoter
TTR (liver)
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV
Shelf Life
12 Months
HS Code
3822190000
UNSPSC Code
41106621
Insert Gene
Cre
Serotype
AAV2/DJ8
Availability
Ready to Ship
Titer
1x10^13 GC/ml
ITRs
AAV2
Reviews of AAV-Ttr-Cre (AAV-DJ8) AAV (AAV/DJ8-Ttr-Cre)