This AAV serotype 5 virus (with Capsid from AAV5 and ITR from AAV2) expresses Cre Recombinase (tagged with nuclear localization sequence) and eGFP marker. Each gene expression is driven by its own CMV promoter. Cre recombinase is a Type I topoisomerase from P1 bacteriophage that catalyzes site-specific recombination of DNA between loxP sites. loxP is a 34 bp DNA sequence at which confers directionality. Cre recombinase is used as a tool to genetically modify genes, such as to delete a segment of DNA flanked by LoxP sites in cultured cells or experimental animals.
Categories
AAV, Over-Expression, Cre Recombinases
Product Type
Pre-Made
Virus Type
AAV
Function
Reporter/Tag
Promoter
CMV (ubiquitous)
Reporter
eGFP
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV
Shelf Life
12 Months
HS Code
3822190000
UNSPSC Code
41106621
Insert Gene
Cre-GFP
Serotype
AAV2/5
Availability
Ready to Ship
Titer
1x10^13 GC/ml
ITRs
AAV2
Reporter
eGFP
Reviews of AAV-Cre-GFP (AAV serotype 5) AAV (AAV5-Cre-GFP)