This AAV serotype 1 virus (with Capsid from AAV1 and ITR from AAV2) expresses Cre Recombinase under the control of a CMV promoter. This Cre contains a nuclear localization signal (NLS).Cre recombinase is a Type I topoisomerase from P1 bacteriophage that catalyzes site-specific recombination of DNA between loxP sites. loxP is a 34 bp DNA sequence at which confers directionality. Cre recombinase is used as a tool to genetically modify genes, such as to delete a segment of DNA flanked by LoxP sites in cultured cells or experimental animals.
Categories
AAV, Over-Expression, Cre Recombinases
Product Type
Pre-Made
Virus Type
AAV
Function
Recombinase
Promoter
CMV (ubiquitous)
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV
Shelf Life
12 Months
HS Code
3822190000
UNSPSC Code
41106621
Insert Gene
Cre
Serotype
AAV2/1
Availability
Ready to Ship
Titer
1x10^13 GC/ml
ITRs
AAV2
Reviews of AAV-Cre (AAV serotype 1) AAV (AAV1-Cre)