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Disease Mice

Shanghai Model Organisms Center, Inc.

Disease Mice

Mouse models are very useful because they share mammalian features with humans and suffer from many of the same diseases. Many mouse models have been created to target specific human diseases using genetic engineering.

  • Lrrtm1-KO

    Lrrtm1-KO

    • Description : Model Descripti
    • Exon : Exon 2
    • Disease : Schizophrenia
    • KI/KO Gene : Lrrtm1
    • Synonyms : AW125451, 46324
  • Ncstn-Flox

    Ncstn-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Nc
    • Exon : Exon s
    • Disease : Chronic Myeloid
    • KI/KO Gene : Ncstn
  • Nrg3-KO

    Nrg3-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Nr
    • Exon : Exon 3
    • Disease : Schizophrenia
    • KI/KO Gene : Nrg3
  • Nphs2-A286V

    Nphs2-A286V

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Np
    • Exon : Exon 3
    • Disease : Hereditary Glom
    • KI/KO Gene : Nphs2
  • Pd-1-KO

    Pd-1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pd
    • Exon : Exon 2-4
    • Application : Immune-Related
    • Disease : Cystitis
  • Nrxn2-KO

    Nrxn2-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Nr
    • Exon : Exon 4-6
    • Application : Immune-Related
    • Disease : Autism Spectrum
  • Phox2a-KO

    Phox2a-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ph
    • Exon : Exon 2
    • Application : Immune-Related
    • Disease : Type 2 Diabetes
  • Ppp1r13l-KO

    Ppp1r13l-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pp
    • Exon : Exon 4-7
    • Application : Immune-Related
    • Disease : Arrhythmogenic
  • Ppm1g-KO

    Ppm1g-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pp
    • Exon : Exon 2-7
    • Application : Immune-Related
    • Disease : Schizophrenia
  • pMMTV-Jag1-Tg(Balb/c)

    pMMTV-Jag1-Tg(Balb/c)

    • Description : Model Descripti
    • Nomenclature : BALB/cAnSmoc-Tg
    • Exon : Exon 2-7
    • Application : Spontaneous Tum
    • Disease : Schizophrenia
  • Prf1-KO

    Prf1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pr
    • Exon : Exon 3
    • Application : Immune-Related
    • Disease : Schizophrenia
  • Pten-KO

    Pten-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pt
    • Exon : Exon 5
    • Application : Cancer Research
    • Disease : Autism Spectrum
  • Pten-Flox

    Pten-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pt
    • Exon : Exon s
    • Application : Cancer Research
    • Disease : Autism Spectrum
  • R26-CAG-LSL-hFGFR2-IRES-Luc-2A-EGFP

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon s
    • Application : Cancer
    • Disease : Autism Spectrum
  • R26-CAG-LSL-hIDH1*R132H-IRES-Luc-2A-tdTomato

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon s
    • Application : Cancer Research
    • Disease : Autism Spectrum
  • R26-CAG-LSL-hFGFR3-IRES-Luc-2A-EGFP

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon s
    • Application : Cancer Research
    • Disease : Autism Spectrum
  • R26-CAG-LSL-hFGFR3*S249C-IRES-Luc-2A-EGFP

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon s
    • Application : Cancer Research
    • Disease : Autism Spectrum
  • R26-CAG-LSL-hTARDBP*A315T-EGFP

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon s
    • Application : Amyotrophic Lat
    • Disease : Autism Spectrum
  • R26-CAG-LSL-hSOD1*G94A-IRES-EGFP

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon s
    • Application : Amyotrophic Lat
    • Disease : Amyotrophic Lat
  • Slc6a3-KO

    Slc6a3-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sl
    • Exon : Exon 4
    • Application : Dwarfism, Nervo
    • Disease : schizophrenia
  • Slc6a1-KO(3)

    Slc6a1-KO(3)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sl
    • Exon : Exon 7.
    • Application : Dwarfism, Nervo
    • Disease : schizophrenia
  • Slc34a1-KO

    Slc34a1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sl
    • Exon : Exon 3-6
    • Application : Research On Min
    • Disease : Hereditary Hypo
  • Srf-Flox

    Srf-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sr
    • Exon : Exon s
    • Application : Research On Min
    • Disease : Dilated Cardiom
  • Snrpn-KO

    Snrpn-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sn
    • Exon : Exon 6
    • Application : Related Researc
    • Disease : Prader-Willi Sy
  • Stat3-Flox(2)

    Stat3-Flox(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-St
    • Exon : Exon 18-20
    • Application : Study On Micror
    • Disease : inflammatory bo