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Disease Mice

Shanghai Model Organisms Center, Inc.

Disease Mice

Mouse models are very useful because they share mammalian features with humans and suffer from many of the same diseases. Many mouse models have been created to target specific human diseases using genetic engineering.

  • Snca-KO

    Snca-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sn
    • Exon : Exon 4
    • Application : Immune-Related,
    • KI/KO Gene : Snca
  • Smarcad1-KO

    Smarcad1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sm
    • Exon : Exon 3
    • Application : Research On Sig
    • Disease : Asphyxiating Th
  • Slc9a9-Flox

    Slc9a9-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sl
    • Exon : Exon s
    • Application : Research On Sig
    • Disease : Autism Spectrum
  • Tsc1-Flox

    Tsc1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ts
    • Exon : Exon 17-18
    • Application : Research On Mto
    • Disease : Tuberous Sclero
  • Trp53inp1-KO

    Trp53inp1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tr
    • Exon : Exon 3
    • Application : Research On Mto
    • Disease : Abdominal Obesi
  • Trp53-KO(2)

    Trp53-KO(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tr
    • Exon : Exon 5-7
    • Application : Cancer Research
    • Disease : Medulloblastoma
  • Xirp1-KO

    Xirp1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Xi
    • Exon : Exon 2
    • Application : Cancer Research
    • Disease : Hypertrophic Ca
  • Ube3a-KO

    Ube3a-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ub
    • Exon : Exon 5
    • Application : Diseases Associ
    • Disease : Angelman Syndro
  • Zap70-W163C(Balb/c)

    Zap70-W163C(Balb/c)

    • Description : Model Descripti
    • Nomenclature : BALB/cAnSmoc-Za
    • Exon : Exon 5
    • Application : Rheumatoid Arth
    • Disease : Rheumatoid Arth
  • Ifngr1/Ifnar1-KO

    Ifngr1/Ifnar1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-If
    • Exon : Exon 5
    • Application : Zika Virus Rese
    • Disease : Rheumatoid Arth
  • hDPP4

    hDPP4

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Dp
    • Exon : Exon 5
    • Application : Mers Infection
    • Disease : Rheumatoid Arth
  • R26-CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luc

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon 5
    • Application : Hpv Research
    • Disease : Rheumatoid Arth
  • R26-hCD46-IRES-tdTomato

    R26-hCD46-IRES-tdTomato

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon 5
    • Application : Immune-Related
    • Disease : Rheumatoid Arth
  • HBV-Tg

    HBV-Tg

    • Description : Model Descripti
    • Nomenclature : B6.Cg-Tg(HBV)Sm
    • Exon : Exon 5
    • Application : Hbv
    • Disease : Rheumatoid Arth
  • hCD81

    hCD81

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Exon : Exon 5
    • Application : Hdv Infection R
    • Disease : Rheumatoid Arth
  • Aire-KO

    Aire-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ai
    • Exon : Exon 8
    • Application : Hdv Infection R
    • Disease : Sjogren's Syndr
  • Ahi1-Flox

    Ahi1-Flox

    • Description : Model Descripti
    • Nomenclature : B6;129S-Ahi1tm1
    • Exon : Exon 2
    • Application : Joubert Syndrom
    • Disease : Sjogren's Syndr
  • Apc-L850X

    Apc-L850X

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ap
    • Exon : Exon 2
    • Application : Heterozygotes O
    • Disease : familial adenom
  • Arhgef10-KO

    Arhgef10-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ar
    • Exon : Exon 5
    • Application : Heterozygotes O
    • Disease : Autism Spectrum
  • Bsn-KO

    Bsn-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Bs
    • Exon : Exon 2
    • Application : Heterozygotes O
    • Disease : Epilepsy
  • Brinp1-KO

    Brinp1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Br
    • Exon : Exon 3
    • Application : Heterozygotes O
    • Disease : Autism Spectrum
  • Casp8-Flox

    Casp8-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ca
    • Exon : Exon s
    • Application : Cancer Research
    • Disease : Autoimmune Lymp
  • Col4a5-R471X

    Col4a5-R471X

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Co
    • Exon : Exon s
    • Application : Alport Syndrome
    • Disease : X-Linked Alport
  • Cldn16-KO

    Cldn16-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cl
    • Exon : Exon 2
    • Application : Sertoli-Sertoli
    • Disease : Renal Hypomagne
  • Cyp19A1-KO

    Cyp19A1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cy
    • Exon : Exon 2
    • Application : Sertoli-Sertoli
    • Disease : Abdominal Obesi