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Disease Mice

Shanghai Model Organisms Center, Inc.

Disease Mice

Mouse models are very useful because they share mammalian features with humans and suffer from many of the same diseases. Many mouse models have been created to target specific human diseases using genetic engineering.

  • Aldh1L2-KO

    Aldh1L2-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Al
    • Exon : Exon 2
    • Disease : Non-Alcoholic F
    • KI/KO Gene : Aldh1l2
  • Akt2-KO

    Akt2-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ak
    • Exon : Exon 3-4
    • Application : Signal Transduc
    • Disease : Type 2 Diabetes
  • Agxt-KO

    Agxt-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ag
    • Exon : Exon 3-8
    • Application : Signal Transduc
    • Disease : Primary Hyperox
  • Adk-KO

    Adk-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ad
    • Exon : Exon 4
    • Application : Signal Transduc
    • Disease : Fatty Liver Dis
  • Alms1-del(c.3802-3812)

    Alms1-del(c.3802-3812)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Al
    • Exon : Exon 4
    • Application : Alström Syndrom
    • Disease : Fatty Liver Dis
  • Bckdk-KO

    Bckdk-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Bc
    • Exon : Exon 9-12
    • Application : Alström Syndrom
    • Disease : Autism Spectrum
  • Braf-Flox-V600E

    Braf-Flox-V600E

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Br
    • Exon : Exon 9-12
    • Application : Cancer Research
    • Disease : Autism Spectrum
  • Braf-Flox

    Braf-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Br
    • Exon : Exon 5
    • Application : Study On The Co
    • Disease : Melanoma
  • Cdyl-Flox

    Cdyl-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Exon : Exon s
    • Application : Study On The Co
    • Disease : Epilepsy
  • Cd200-KO

    Cd200-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Exon : Exon 2
    • Application : Immune-Related
    • Disease : Epilepsy
  • Cox10-Flox

    Cox10-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Co
    • Exon : Exon s
    • Application : Immune-Related
    • Disease : Parkinson's Dis
  • Cntnap2-KO

    Cntnap2-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cn
    • Exon : Exon 4
    • Application : Immune-Related
    • Disease : Cortical Dyspla
  • Chst3-KO

    Chst3-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ch
    • Exon : Exon 4
    • Application : Immune-Related
    • Disease : Schizophrenia
  • Cenpf-Flox

    Cenpf-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ce
    • Exon : Exon 3
    • Application : Immune-Related
    • Disease : Dilated Cardiom
  • Cyp4v3-KO

    Cyp4v3-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cy
    • Exon : Exon 2-6
    • Application : Immune-Related
    • Disease : Bietti Crystall
  • Dicer1-Flox

    Dicer1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Di
    • Exon : Exon 23
    • Application : Hypoxia-Mediate
    • Disease : Ovarian Cancer
  • F8-KO

    F8-KO

    • Description : Model Descripti
    • Nomenclature : B6.129S-F8tm1Sm
    • Exon : Exon 16-19.
    • Application : Hemophilia A;He
    • Disease : Factor Viii Def
  • Eif4ebp2-KO

    Eif4ebp2-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ei
    • Exon : Exon 3-4
    • Application : Cell Proliferat
    • Disease : Autism Spectrum
  • Efhc1-KO

    Efhc1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ei
    • Exon : Exon 3-5
    • Application : Cell Proliferat
    • Disease : Juvenile Myoclo
  • Drd2-KO

    Drd2-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Dr
    • Exon : Exon 3
    • Application : Immune-Related
    • Disease : Juvenile Myoclo
  • F9-KO

    F9-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-F9
    • Exon : Exon 8
    • Application : Factor Ix (F9)
    • Disease : Hemophilia B
  • Gata5-KO

    Gata5-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ga
    • Exon : Exon 2
    • Application : Factor Ix (F9)
    • Disease : Essential Hyper
  • Gabrb3-KO

    Gabrb3-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ga
    • Exon : Exon 2-3
    • Application : Factor Ix (F9)
    • Disease : Autism Spectrum
  • Ghr-KO

    Ghr-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gh
    • Exon : Exon 4.
    • Application : Cardiovascular
    • Disease : Laron Syndrome
  • Gstm1-KO

    Gstm1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gs
    • Exon : Exon 2
    • Application : Cardiovascular
    • Disease : Autism Spectrum