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Disease Mice

Shanghai Model Organisms Center, Inc.

Disease Mice

Mouse models are very useful because they share mammalian features with humans and suffer from many of the same diseases. Many mouse models have been created to target specific human diseases using genetic engineering.

  • Adcy5-KO

    Adcy5-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ad
    • Exon : Exon 3
    • Disease : Parkinson's Dis
    • KI/KO Gene : Adcy5
  • Apoe-KO(2)

    Apoe-KO(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ap
    • Exon : Exon 2-4.
    • Application : Atherosclerosis
    • Disease : Coronary Artery
  • Apc-Flox

    Apc-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ap
    • Exon : Exon 15
    • Application : Intestinal Tumo
    • Disease : Colorectal Canc
  • Aldh7A1-KO

    Aldh7A1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Al
    • Exon : Exon 2-5
    • Application : Intestinal Tumo
    • Disease : Pyridoxine-Depe
  • Aldh5a1-KO

    Aldh5a1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Al
    • Exon : Exon 3-7
    • Application : Intestinal Tumo
    • Disease : Epilepsy
  • Arntl-Flox

    Arntl-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ar
    • Exon : Exon 8
    • Application : Studies On The
    • Disease : Diabetes Mellit
  • C1qa-KO

    C1qa-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-C1
    • Exon : Exon 3
    • Application : Studies On The
    • Disease : Epilepsy
  • Brca2-Flox

    Brca2-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Br
    • Exon : Exon 11
    • Application : Breast Cancer R
    • Disease : Breast Cancer
  • Cdkl5-KO

    Cdkl5-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Exon : Exon 6
    • Application : Breast Cancer R
    • Disease : Developmental A
  • Cav1-KO

    Cav1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ca
    • Exon : Exon 3
    • Application : Tumor Suppressi
    • Disease : Alzheimer's Dis
  • C9orf72-KO

    C9orf72-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-C9
    • Exon : Exon 4-5
    • Application : Tumor Suppressi
    • Disease : Autoimmune Dise
  • Chrna7-KO

    Chrna7-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ch
    • Exon : Exon 4
    • Application : Tumor Suppressi
    • Disease : Schizophrenia
  • Cyb5r4-KO

    Cyb5r4-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cy
    • Exon : Exon 3
    • Application : Tumor Suppressi
    • Disease : Type 2 Diabetes
  • Ctnnb1-Flox

    Ctnnb1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ct
    • Exon : Exon 2-6
    • Application : Microrna And Cd
    • Disease : Autism Spectrum
  • Csmd1-KO

    Csmd1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cs
    • Exon : Exon 8
    • Application : Microrna And Cd
    • Disease : Schizophrenia
  • Cplx2-KO

    Cplx2-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cp
    • Exon : Exon 3
    • Application : Microrna And Cd
    • Disease : Schizophrenia
  • Dot1l-Flox

    Dot1l-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Do
    • Exon : Exon s
    • Application : Microrna And Cd
    • Disease : Dilated Cardiom
  • Dnm1-KO

    Dnm1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Dn
    • Exon : Exon 2
    • Application : Microrna And Cd
    • Disease : Idiopathic Gene
  • Erbb2-Flox

    Erbb2-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Er
    • Exon : Exon 2
    • Application : Microrna And Cd
    • Disease : Breast Cancer
  • Egln1-Flox

    Egln1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Eg
    • Exon : Exon 2-3
    • Application : Microrna And Cd
    • Disease : Cardiomyopathy
  • Flvcr1-Flox

    Flvcr1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Fl
    • Exon : Exon 3
    • Application : Diseases Associ
    • Disease : Diamond-Blackfa
  • Fgf23-R176Q

    Fgf23-R176Q

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Fg
    • Exon : Exon 3
    • Application : Hypophosphatemi
    • Disease : Hypophosphatemi
  • Fbn1-C1041G

    Fbn1-C1041G

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Fb
    • Exon : Exon 3
    • Application : Hypophosphatemi
    • Disease : Marfan Syndrome
  • Galt-KO

    Galt-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ga
    • Exon : Exon 3-9
    • Application : Galactosemia Re
    • Disease : Galactosemia
  • Gaa-KO

    Gaa-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ga
    • Exon : Exon 3
    • Application : Immune-Related
    • Disease : Galactosemia